Acetyl-l-carnitine is an acetylated form of the amino acid l-carnitine. Both these compounds she a similarity but differ in their functionalities.
Acetyl-L-carnitine is naturally found inside the body that helps i the better energy production by the mitochondria. This compound facilitates the availability of enzyme acetyl CoA, a metabolite required in the mitochondrial energy production. The cell membrane stability and a healthy functioning of this system is ensured by acetyl-L-carnitine. In addition to this, the acetyl group in this compound in released and used for the formation of a neuro-transmitter- acetylcholine, that is important for mental functions.
Studies done on Acetyl-L-carnitine
A one year study done on the efficacy if acetyl-l-carnitine on 130 elders showed that the product is supportive to the cerebral activities, memory strengthening and improves concentration of the mind. Another short term study conducted on the actions of acetyl-L-carnitine shows its efficacy in the above said areas and also in the behavioral as well as emotional health improvement.
Acetyl-L-Carnitine For Cognitive & Memory Support
Acetyl-L-carnitine is naturally found inside the body that helps in the better energy production by the mitochondria. It is also helpful in removing the waste products from the body. The help of Acetyl-L-carnitine in the fatty acid metabolism is essential for many other processes like energy production, heart and nervous system health, muscle movements etc.
How does Acetyl-L-carnitine work?
Acetyl-L-carnitine helps the body get the gate acids into the mitochondria for their metabolism. Many of the body metabolic activities rely on the fatty acid breakdown and without the acetyl-l-carnitine, this cannot be possible. It is also helpful in removing the waste products from the body. In the presence of high levels of Acetyl-L-carnitine, the kidney will more readily remove the wastes and in the opposite condition, the process will be sluggish and kidneys retain the waste within. The help of Acetyl-L-carnitine in the fatty acid metabolism is essential for many other processes like energy production, heart and nervous system health, muscle movements etc.
In addition to these, the acetyl group in this compound is useful for the production of some neuro-transmitter – acetylcholine, which ensures the nervous functions as well. This particular use will make it useful in the treatment of many nervous disorders.
Pure Acetyl-Lcarnitine 500 mg capsules ingredients
The ingredients of Pure Acetyl-L-carnitine are –
- Vitamin C in the form of ascorbic acid.
- The main active ingredient is the acetylated form of L-carnitine, improves the brain and cerebral functions and provide more energy by increasing the fat metabolism in mitochondria.
- The vitamin C is an additional ingredient that enhances the activities of the main ingredient- acetyl-L-carnitine. The presence of vitamin C is essential for the synthesis of carnation. The acetyl-L-carnitine makes the availability of co enzyme acetyl CoA, which is essential for the mitochondrial function. The capsule is made with hypoallergenic plant fibre. This finer is added to add to the volume.
The recommended dosage of acetyl-L-carnitine is 1–2 capsules everyday day. It can be divided doses. It must be taken between meals or as directed by your doctor. It is recommended to take along with the breakfast and lunch and not with the diner or evening meals. The product may interfere with the sleep patterns and can delay sleep. Taking the capsules with the meals can reduce the gastrointestinal related side effects. Do not take excess dosage less recommended by the doctor, the overdose can cause serious effects.
The changes may start showing within a month or least by 2-3 months. It is safe for a long term usage and fits well with all adults, young or old.
Acetyl L-carnitine is a great dietary supplement that can help with almost all department of our lives. It provides better mental and physical health. IT improves memory, concentration, alertness, more energy etc. Acetyl L-carnitine is an only amino acid that can cross the blood brain barrier and help in the nerve cells regeneration. This single act works wonder inside the brain and the parts of the body.
Acetyl L-carnitine can prevent the hardening of the arteries and thereby provide better space inside the arteries that result in reduced blood pressure. the nerve protection property of this compound helps in diabetes. Long term diabetes can damage the nerve cells, the same can be prevented by acetyl L-carnitine.
It is also beneficial in weight loss and bodybuilding. It helps the body fund stored fat as an alternate energy source and indirectly help with weight loss. Acetyl L-carnitine is required for the mitochondria to metabolite the fatty acids that help in more energy. This extra energy helps in enduring the workouts. The nerve protection also helps in preventing muscle damage and their recovery period.
What are the side effects of using Acetyl-L-carnitine?
Acetyl-L-carnitine does not have any major side effects that one needs to concerned about. The minor side effects include nausea, vomiting, skin rashes, diarrhoea, increase in appetite, unpleasant body odor, a fishy smelling urine, sweat or breath etc. All these are due to the changes happening in the metabolic processes and the elimination of many waste products from the body.
None of these is effects will be long lasting, it will disappear in a few days and are mostly seen in the initial days of dosage. There also are certain drugs which when used along with Acetyl-L-carnitine may cause certain side effects, such drugs are chemotherapy drugs, that for HIV and cancer treatment drugs.
Pregnant women, nursing mothers, people having seizures should not take acetyl-L-carnitine as there could be unexpected effects. People having liver cirrhosis, kidney failure, hepatitis C etc should also stay away from this dietary supplement.
Buying Acetyl-L-carnitine online
Acetyl-L carnitine 500 mg capsules are available to purchase online from Amazon and other online stores. You can have it from the Dr.Hyman’s store as well. The 500 mg capsules are available in bottle with 60 capsules.
The reviews of this product shows that it is quite effective. Despite the fact that the dosage here is much lower than many other n brands, this Pure Acetyl-L-carnitine seems to have made an impression among the users. most customers are happy with the happy feeling and the increased energy levels. The weight loss has happened as an additional advantage. There has also been less of the possible side effects mentioned.
Athletes who have tried this has got longer endurance. The duration of the workouts have also been improved with time. The ability to concentrate more has surprised many. People who have used it for weight loss have also found it positive.
The price of this product has mixed reviews. Some feel it is underrated for its use while others feel it as a little higher.
Acetyl-L carnitine and OCD and ADHD
Obsessive compulsive disorder – OCD is an anxiety disorder and ADHD is hyper activity. The treatment for these disorders has categorised Acetyl-L-carnitine as a medical complement, which helps strengthen other therapies. Acetyl-L-carnitine can improve the effects of the medicines used for such conditions and can also reduce the impact of side effects caused by them. Regular small dosage of acetyl L-carnitine can improve the effects of the OCD and ADHD medicines and reduce their dose also.
There is a significant connection between the fatty acid metabolism and nerve insulation, acetyl L-carnitine can also do more advantages in controlling OCD and ADHD. Since both the disorders are connected to the brain and nerves, this single solution can work for both. Moreover, the ability of acetyl L-carnitive in improving concentration helps reduce many symptoms of ADHD.
Is acetyl-L-carnitine useful for bodybuilding?
Acetyl L-carnitine is useful in bodybuilding, but not the same way L-carnitine does. Acetyl L-carnitine serves as a protection against the exercise damage to the cells. There is a considerable reduction in the damaged cells during the workouts. It also helps in facilitating smoother fat metabolism. It can also prevent muscle contractions. The oxidation of muscle is lesser and the recovery period is also lessened. Acetyl L-carnitine is also know to provide more energy that helps in enduring the longest workouts. It can spare the glycogen from taking as an alternative energy source and reduce the lactic acid accumulation, which happens as a by product in glucose metabolism.
Acetyl-L-carnitine for brain health
Acetyl L-carnitine is good for the brain health. The effects of this compound improve the memory, a positive mood and elevated levels of energy – of both mental and physical. Users have also found it to be improving the concentration power. All these are because of the neuro-protective nature of the acetyl L-carnitine. The increased production of acetylcholine is good for memory. Acetyl L carnation is also useful in improved levels of serotonin and the noradrenaline. All these together work to have elevated health levels in the brain.
Acetyl-L-carnitine can aid in nerve regeneration
Nerve regeneration is not an easy process and rare as well. A damaged nerve cells makes gap in between the nerve communication and leads to nervous disorders of any kind. Since these nerve cells cannot divide to fill in the gap, some new cells has to be formed and reach there to do that job. There are not many compounds that can do this and luckily, Acetyl-L-carnitine is one of them. This compound can work on the regenerate the myelin sheet of the nerve cells and make new nerve fibres. This improves their functions and reconnects the nerves with organs. The analgesic property of the acetyl-L-carnitine is because of this nerve regeneration ability.
What is the connection between Acetyl-L-carnitine and blood pressure?
It is seen in many cases that Acetyl-L-carnitine has lowered the blood pressure. There re no scientific proof to back up this claim. The acetyl-L-carnitine increases the diameter of the brachial artery that allows free flow of the blood ad thus lowering the blood pressure which was a little higher. This is seen mostly in people with metabolic syndrome. They will have high blood pressure due to insulin sensitivity and high cholesterol levels. With acetyl-L-carnitine, they get relief from the blood pressure as well as got a stabilized blood sugar level. This was found in an Italian research that ran for about 24 weeks.
Acetyl-L-carnitine and its effect on hyperthyroidism
Hyperthyroidism is an over active thyroid glands. This condition makes the body deprived of carnatine and increases its need. It happens that under hyperthyroidism, the body increases its loss of carnation though the urine. By adding the most effective form of carnitine, acetyl-Lcarnitine, the body gets natural supply of the same. Acetyl L-carnitine can prevent the muscle weakness, and nervousness. Acetyl-L-carnitine protects the muscles and regenerate any damaged nerves and improve the energy levels. It can prevent the burning of fat cells by muscle cells and reduce the thyroid activity.
Acetyl-L-carnitine drug interactions
Acetyl-L-carnitine has some major drug interactions with a few. It should not be taken with an anti-coagulant. Acetyl-L-carnitine can increase the drug’s effect making the blood clotting utterly slow which may cause troubles.
It can also affect the blood sugar lowering drugs and alter their effectiveness. Care must also be taken when the person is on any other herbal supplement, as acetyl-l-carnitine has some interactions with certain herbs as well. It is always safer to consult with the doctor before taking this dietary supplement.
As a positive drug interaction,using acetyl-l-carnitine with an anticonvulsant medication vampiric acid can minimize the side effect of that drug. As a side effect it lowers the carnation level in the body and by taking acetyl-l-carnitine, the deficiency can be countered.
What are the natural sources for Acetyl-L-carnitine?
The natural resources of acetyl-l-carnitine is animal based foods. Beef, chicken, milk, cheese and fishes are the best natural sources for acetyl-l-carnitine. The red meat in mutton is the principle source for this amino acid derivative. Lean beef is the best choice. Among the fishes, shellfish has the largest amount of carnitine. Chicken breast is good as well. It can provide protein, vitamins and minerals also. 4 ounces of chicken breast has 3-4 mg of carnitine. The shellfish has 4-7 mg, and low fat pork contains 24 mg of this amino acid.
Acetyl-L-carnitine shelf life and storage
Acetyl-L-carnitine is stored at room temperature and away from the heat and sunlight. Excess moisture can damage the potency and effectiveness of the product and can damage it. When stored under favorable conditions, Acetyl-L-carnitine, 500 mg capsules have a shelf life of up to 2 years without fail.
How effective is Acetyl-L-carnitine for weight loss?
The weight loss heroines as a secondary process of using acetyl L-carnitine. This amino acid derivative can transport the fatty acids into the mitochondria for their metabolism. This intern improves the body’s overall ability in burning fat. This utilization of the fat cells reduce the body weight. It forces more fatty acids into the mitochondria. This improves the metabolic rate and more and more fat cells are broken down helping in gradual weight loss. It is helpful for those who are trying hard with a controlled diet to lose weight.
Acetyl-L-carnitine and insomnia
Insomnia is considered as a side effect of using acetyl-L-carnitine. It is also recommended not to use this supplement in the evening or at night as it may cause sleep disruptions. Though it can control the nerves and bring a bit of calmness, it cannot promote sleep, but does the opposite.
How does Acetyl-L-Carnitine increase the energy?
Acetyl L-carnitine transports more fatty acids into the power house of the cell- mitochondria. These fatty acids are broken down to provide energy. As more and more fat cells are transported and broken down, the energy level is also increased. Fat cells are the biggest source of energy and this amino acid make sure that the body reaches for the stored fat for energy rather than the glycogen. This also increase the metabolic rate inside the body that results in an increased energy levels. It is especially helpful for ageing people to maintain their energy levels and lead a youthful life for longer.